TAED entry 4 from Master Catalog version 2.1x family 28013 is ACTH receptor.
Ka/Ks > 0.6 has been measured along the branch between Amniota and Eutheria.
The information from EGAD is appended below:
This TAED entry has sequence similarity to EGAD entry:
HT27424 melanocortin receptor , with a known function in: cell signaling/cell communication.
HT27424 melanocortin receptor , with a known function in: receptors/cell signaling.
The information from PMD is appended below:
This TAED entry has sequence similarity to PMD entry: A940011
Protein=Adrenocorticotropic hormone (ACTH) receptor
Source=Human
genotype 1-Ser 74 Ile
genotype 2-Pro 27 Arg
genotype 3-Ile 44 MetLeu 192 (frameshift) (other allele)
genotype 4-Ser 74 Ile Arg 128 Cys (other allele)
phenotype1-Familial glucocorticoid deficiency
phenotype2-Familial glucocorticoid deficiency
phenotype3-Familial glucocorticoid deficiency
phenotype4-Familial glucocorticoid deficiency