TAED entry 1 from Master Catalog version 2.1x family 20390 is protein tyrosine phosphatase.
Ka/Ks > 0.6 has been measured following species specific evolution within Homo sapiens.
Structural information is available for this entry.
The information from EGAD is appended below:
This TAED entry has sequence similarity to EGAD entry:
HT27831 tyrosine phosphatase, receptor, sigma , with a known function in: cell signaling/cell communication.
HT27831 tyrosine phosphatase, receptor, sigma , with a known function in: receptors/cell signaling.
The information from PMD is appended below:
This TAED entry has sequence similarity to PMD entry: A910831
Protein=Tyrosine phosphatase LAR (Leukocyte antigen-related protein), domain I (Gly--Met 1275-1613)
Source=Human
genotype 1-Arg 1354 His
genotype 2-Asp 1362 Asn
genotype 3-Ala 1382 Val
genotype 4-Gly 1399 Asp
genotype 5-Pro 1400 Leu
genotype 6-Arg 1425 Trp
genotype 7-Cys 1434 Tyr
genotype 8-Gly 1447 Ser
genotype 9-Thr 1461 Ile
genotype 10-Gly 1473 Ser
genotype 11-Asp 1490 Asn
genotype 12-Pro 1494 Ser
genotype 13-Gly 1516 Arg
genotype 14-Val 1519 Met
genotype 15-Ser 1523 Asn
genotype 16-Ala 1524 Thr
genotype 17-Arg 1528 Cys
genotype 18-Glu 1540 Lys
genotype 19-Gln 1570 (termination)
genotype 20-Gln 1296 (termination)
genotype 21-Arg 1558 (termination)
genotype 22-Gln 1436 (termination)
genotype 23-Trp 1413 (termination)
genotype 24-Gln 1560 (termination)
genotype 25-Trp 1409 (termination)
genotype 26-Gln 1484 (termination)
genotype 27-Gly 1399 Asp
genotype 28-Arg 1528 Cys
genotype 29-Gln 1415 (termination)
genotype 30-Gln 1398 (termination)
genotype 31-Gln 1391 (termination)
genotype 32-Thr 1397 Met
genotype 33-Cys 1446 Tyr
genotype 34-Leu 1368 Phe
genotype 35-Glu 1329 Lys
genotype 36-Asp 1407 Asn
genotype 37-Gly 1387 Asp
genotype 38-Met 1486 Thr
genotype 39-Tyr 1379 Phe
genotype 40-Glu 1329 Lys
genotype 41-Leu 1368 Phe
genotype 42-Tyr 1379 Phe
genotype 43-Gly 1387 Asp
genotype 44-Thr 1397 Met
genotype 45-Asp 1407 Asn
genotype 46-Cys 1446 Tyr
genotype 47-Asp 1362 AsnCys 1446 Tyr
genotype 48-Glu 1329 LysCys 1446 Tyr
genotype 49-Leu 1368 PheCys 1446 Tyr
genotype 50-Gly 1387 AspCys 1446 Tyr
genotype 51-Met 1486 Thr
genotype 52-Asp 1362 AsnMet 1486 Thr
genotype 53-Cys 1446 TyrMet 1486 Thr
phenotype1-Protein tyrosine phosphatase (PTPase) activity at 25 C [- -], at 37 C [- -], and at 42 C [0]
phenotype2-Thermal stability [- - -]
phenotype3-PTPase activity at 25 C [=], at 37 C [-], and at 42 C [- -]
phenotype4-Thermal stability [- -]
phenotype5-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype6-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype7-PTPase activity at 25 C [- -], at 37 C [0], and at 42 C [0]
phenotype8-Thermal stability [- -]
phenotype9-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype10-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype11-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype12-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype13-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype14-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype15-PTPase activity at 25 C [- -], at 37 C [- -], and at 42 C [- -]
phenotype16-PTPase activity at 25 C [- -], at 37 C [- -], and at 42 C [- -]
phenotype17-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype18-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype19-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype20-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype21-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype22-PTPase activity at 25 C [0], at 37 C [0], and at 42 C [0]
phenotype23-PTPase activity at 37 C [-]
phenotype24-PTPase activity at 37 C [-]
phenotype25-PTPase activity at 37 C [-]
phenotype26-PTPase activity at 37 C [-]
phenotype27-PTPase activity at 37 C [-]
phenotype28-PTPase activity at 37 C [-]
phenotype29-PTPase activity at 37 C [-]
phenotype30-PTPase activity at 37 C [-]
phenotype31-PTPase activity at 37 C [-]
phenotype32-PTPase activity at 37 C [-]
phenotype33-PTPase activity at 37 C [-]
phenotype34-PTPase activity at 37 C [-]
phenotype35-PTPase activity at 37 C [-]
phenotype36-PTPase activity at 37 C [-]
phenotype37-PTPase activity at 37 C [-]
phenotype38-PTPase activity at 37 C [-]
phenotype39-PTPase activity at 37 C [-]
phenotype40-PTPase activity at 37 C [-]
phenotype41-PTPase activity at 37 C [-]
phenotype42-PTPase activity at 37 C [-]
phenotype43-PTPase activity at 25 C [=], at 37 C [-], and at 42 C [-]
phenotype44-Thermal stability [- -]
phenotype45-PTPase activity at 25 C [-], at 37 C [- -], and at 42 C [-]
phenotype46-Thermal stability [- -]
phenotype47-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [-]
phenotype48-Thermal stability [- -]
phenotype49-PTPase activity at 25 C [-], at 37 C [-], and at 42 C [- -]
phenotype50-Thermal stability [- -]
phenotype51-PTPase activity at 25 C [=], at 37 C [-], and at 42 C [- -]
phenotype52-Thermal stability [- -]
phenotype53-PTPase activity at 25 C [=], at 37 C [-], and at 42 C [-]
phenotype54-Thermal stability [- -]
phenotype55-PTPase activity at 25 C [+], at 37 C [+], and at 42 C [+]
phenotype56-Thermal stability [+]
phenotype57-Folding efficiency [+]
phenotype58-PTPase activity at 25 C [+], at 37 C [+], and at 42 C [=]
phenotype59-Thermal stability [-]
phenotype60-PTPase activity at 25 C [+ +], at 37 C [+], and at 42 C [+]
phenotype61-Thermal stability [-]
phenotype62-PTPase activity at 25 C [+], at 37 C [+], and at 42 C [-]
phenotype63-Thermal stability [-]
phenotype64-PTPase activity at 25 C [+], at 37 C [+], and at 42 C [=]
phenotype65-Thermal stability [-]
phenotype66-PTPase activity at 25 C [+], at 37 C [+], and at 42 C [+]
phenotype67-Thermal stability [=]
phenotype68-PTPase activity at 25 C [=], at 37 C [=], and at 42 C [- -]
phenotype69-Thermal stability [- -]
phenotype70-PTPase activity at 25 C [+], at 37 C [+], and at 42 C [+]
phenotype71-Thermal stability [+]