TAED entry 1 from Master Catalog version 2.1x family 13012 is interleukin-6-receptor.
Ka/Ks > 0.6 has been measured along the branch between Amniota and Eutheria.
Structural information is available for this entry.
The information from EGAD is appended below:
This TAED entry has sequence similarity to EGAD entry:
HT28626 interleukin-11 receptor, alpha chain, alt. transcript 2 , with a known function in: cell signaling/cell communication.
HT28626 interleukin-11 receptor, alpha chain, alt. transcript 2 , with a known function in: receptors/cell signaling.
The information from PMD is appended below:
This TAED entry has sequence similarity to PMD entry: A931464
Protein=Interleukin-6 receptor, soluble extracellular portion (Met--Leu 1-344) (sIL-6R)
Source=Human
genotype 1-Val-Pro 112-113 Gly-Thr
genotype 2-Cys-Phe 121-122 Ala-Gly
genotype 3-Cys 121 Ser
genotype 4-Phe 122 Ala
genotype 5-Arg-Lys 123-124 Gln-Ser
genotype 6-Ser-Pro 125-126 Ile-Ser
genotype 7-Asn-Val 129-130 Lys-Leu
genotype 8-Cys 132 Ala
genotype 9-Trp 134 Leu
genotype 10-Gly-Pro 135-136 Ser-Thr
genotype 11-Pro 140 Gly
genotype 12-Thr-Thr-Lys 143-145 Gly-Ala-Glu
genotype 13-Lys-Ala 145-146 Arg-Pro
genotype 14-Phe 153 Leu
genotype 15-Glu-Asp 159-160 Leu-Gly
genotype 16-Asp-Phe 160-161 Glu-Leu
genotype 17-Gln-Glu 162-163 Leu-Gln
genotype 18-Cys 165 Leu
genotype 19-Tyr-Ser 167-168 Ser-Thr
genotype 20-Gln-Lys 172-173 Leu-Gln
genotype 21-Phe 174 Ile
genotype 22-Cys 176 Ala
genotype 23-Pro-Glu 181-182 Leu-Gln
genotype 24-Asp 184 Thr
genotype 25-Val 190 Gly
genotype 26-Cys 193 Asp
genotype 27-Lys-Phe 201-202 Met-Leu
genotype 28-Lys-Phe 201-202 Glu-Leu
genotype 29-Lys-Thr 204-205 Arg-Ser
genotype 30-Cys 211 Ala
genotype 31-Gly-Ile 212-213 Glu-Phe
genotype 32-Asp 217 Val
genotype 33-Pro-Pro 218-219 Ala-His
genotype 34-Ala-Asn 220-221 Val-Asp
genotype 35-Arg 232 Ser
genotype 36-Trp 233 Gln
genotype 37-Val 236 SerTrp 238 Leu
genotype 38-Ser-Phe 247-248 Ala-Val
genotype 39-Arg-Leu 250-251 Ser-Ile
genotype 40-Glu 254 Ala
genotype 41-Glu-Leu 254-255 Val-His
genotype 42-Arg-Tyr 256-257 Ser-Asp
genotype 43-Glu-Arg 260-261 Ala-Gly
genotype 44-Arg-Ser-Lys 261-263 Gly-Ala-Gly
genotype 45-Lys-Asp 271-272 Arg-Tyr
genotype 46-Gln-His 274-275 Leu-Gln
genotype 47-Cys 277 Asp
genotype 48-Val-Ile 278-279 Gly-Met
genotype 49-Val 278 Asn
genotype 50-Ile 279 Asp
genotype 51-His-Asp 280-281 Ser-Gly
genotype 52-His 280 Ile
genotype 53-Asp-Ala 281-282 Val-Asp
genotype 54-Asp 281 Gly
genotype 55-Gly 285 Asp
genotype 56-Arg-His 287-288 Ala-Ile
genotype 57-His-Val 288-289 Tyr-Leu
genotype 58-Val-Gln 290-291 Met-His
genotype 59-Gln 291 Lys
genotype 60-Arg 293 Gly
genotype 61-Arg-Ala 293-294 Gly-Thr
genotype 62-Glu-Phe 297-298 Ala-Ile
genotype 63-Gly-Glu 301-302 Val-Asp
genotype 64-Trp-Ser 303-304 His-Ala
genotype 65-Ser 304 AlaSer 307 Ala
genotype 66-Glu-Trp 305-306 Asp-Arg
genotype 67-Pro-Glu 308-309 Leu-Gln
genotype 68-Thr-Pro 313-314 Lys-Leu
genotype 69-Glu-Ser-Arg 317-319 Val-Val-Gly
genotype 70-Ser-Pro 320-321 Asn-Ser
phenotype1-Secretion [=]
phenotype2-Interleukin-6 (IL-6) binding [=]: Potential to mediate the IL-6 signal [=]
phenotype3-Secretion [=]
phenotype4-IL-6 binding [- -]
phenotype5-Secretion [=]
phenotype6-IL-6 binding [0]
phenotype7-Secretion [=]
phenotype8-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype9-Secretion [=]
phenotype10-IL-6 binding [- -]
phenotype11-Secretion [=]
phenotype12-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype13-Secretion [=]
phenotype14-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype15-Secretion [=]
phenotype16-IL-6 binding [- -]
phenotype17-Secretion [=]
phenotype18-IL-6 binding [- -]
phenotype19-Secretion [=]
phenotype20-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype21-Secretion [=]
phenotype22-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype23-Secretion [=]
phenotype24-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype25-Secretion [=]
phenotype26-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype27-Secretion [=]
phenotype28-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype29-Secretion [=]
phenotype30-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype31-Secretion [=]
phenotype32-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype33-Secretion [=]
phenotype34-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype35-Secretion [=]
phenotype36-IL-6 binding [0]
phenotype37-Secretion [=]
phenotype38-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype39-Secretion [=]
phenotype40-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype41-Secretion [=]
phenotype42-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype43-Secretion [=]
phenotype44-IL-6 binding [0]
phenotype45-Secretion [=]
phenotype46-IL-6 binding [- -]
phenotype47-Secretion [=]
phenotype48-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype49-Secretion [=]
phenotype50-IL-6 binding [=]: Potential to mediate the IL-6 signal [0]
phenotype51-Secretion [=]
phenotype52-IL-6 binding [- -]
phenotype53-Secretion [=]
phenotype54-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype55-Secretion [=]
phenotype56-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype57-Secretion [=]
phenotype58-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype59-Secretion [=]
phenotype60-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype61-Secretion [=]
phenotype62-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype63-Secretion [=]
phenotype64-IL-6 binding [- -]
phenotype65-Secretion [=]
phenotype66-IL-6 binding [0]
phenotype67-Secretion [=]
phenotype68-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype69-Secretion [=]
phenotype70-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype71-Secretion [=]
phenotype72-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype73-Secretion [=]
phenotype74-IL-6 binding [0]
phenotype75-Secretion [=]
phenotype76-IL-6 binding [0]
phenotype77-Secretion [=]
phenotype78-IL-6 binding [0]
phenotype79-Secretion [=]
phenotype80-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype81-Secretion [=]
phenotype82-IL-6 binding [0]
phenotype83-Secretion [=]
phenotype84-IL-6 binding [0]
phenotype85-Secretion [=]
phenotype86-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype87-Secretion [=]
phenotype88-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype89-Secretion [=]
phenotype90-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype91-Secretion [=]
phenotype92-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype93-Secretion [=]
phenotype94-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype95-Secretion [=]
phenotype96-IL-6 binding [0]
phenotype97-Secretion [=]
phenotype98-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype99-Secretion [=]
phenotype100-IL-6 binding [0]
phenotype101-Secretion [=]
phenotype102-IL-6 binding [=]: Potential to mediate the IL-6 signal [0]
phenotype103-Secretion [=]
phenotype104-IL-6 binding [=]: Potential to mediate the IL-6 signal [- -]
phenotype105-Secretion [=]
phenotype106-IL-6 binding [=]: Potential to mediate the IL-6 signal [0]
phenotype107-Secretion [=]
phenotype108-IL-6 binding [=]: Potential to mediate the IL-6 signal [- -]
phenotype109-Secretion [=]
phenotype110-IL-6 binding [=]: Potential to mediate the IL-6 signal [0]
phenotype111-Secretion [=]
phenotype112-IL-6 binding [- -]
phenotype113-Secretion [=]
phenotype114-IL-6 binding [=]: Potential to mediate the IL-6 signal [- -]
phenotype115-Secretion [=]
phenotype116-IL-6 binding [0]
phenotype117-Secretion [=]
phenotype118-IL-6 binding [- -]
phenotype119-Secretion [=]
phenotype120-IL-6 binding [0]
phenotype121-Secretion [=]
phenotype122-IL-6 binding [0]
phenotype123-Secretion [=]
phenotype124-IL-6 binding [0]
phenotype125-Secretion [=]
phenotype126-IL-6 binding [0]
phenotype127-Secretion [=]
phenotype128-IL-6 binding [0]
phenotype129-Secretion [=]
phenotype130-IL-6 binding [0]
phenotype131-Secretion [=]
phenotype132-IL-6 binding [0]
phenotype133-Secretion [=]
phenotype134-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype135-Secretion [=]
phenotype136-IL-6 binding [0]
phenotype137-Secretion [=]
phenotype138-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]
phenotype139-Secretion [=]
phenotype140-IL-6 binding [=]: Potential to mediate the IL-6 signal [=]