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NucPred - Orthologous groups of (predicted) nuclear proteins

This table gives links to further tables which list orthologous groups of proteins predicted to be nuclear. The idea here is that a nuclear localisation prediction for a protein will be more credible if homologues of that protein in other organisms (which are believed to perform a very similar function) are also predicted to be nuclear. Multiple alignments are also provided to allow a more detailed analysis of the conservation of function across species. We have used the program InParanoid to define orthologous relationships between the human proteome and other proteomes.

Only proteins that are not currently annotated with a nuclear location
Prediction criteria
(number of human proteins)
human
mouse
human
mouse
fly
worm
human
mouse
fly
worm
cerevisiae
pombe
human
mouse
fly
worm
arabidopsis
human
mouse
fly
worm
arabidopsis
cerevisiae
pombe
NucPred ≥ 0.5
(6764)
3098 398 39 130 24
NucPred ≥ 0.8
(2523)
1059 105 3 31 3
NucPred ≥ 0.9
(1255)
492 38 1 13 1
NucPred ≥ 0.9 AND
PredictNLS AND
PSORT II predicted nuclear
(549)
188 11 0 2 0
NucPred ≥ 0.95
(624)
218 8 0 3 0
Including proteins currently annotated with a nuclear location
Prediction criteria
(number of human proteins)
human
mouse
human
mouse
fly
worm
human
mouse
fly
worm
cerevisiae
pombe
human
mouse
fly
worm
arabidopsis
human
mouse
fly
worm
arabidopsis
cerevisiae
pombe
NucPred ≥ 0.5
(9199)
4755 670 171 273 136
NucPred ≥ 0.8
(3593)
1772 199 43 77 33
NucPred ≥ 0.9
(1840)
859 92 13 29 8
NucPred ≥ 0.9 AND
PredictNLS AND
PSORT II predicted nuclear
(901)
398 35 3 12 3
NucPred ≥ 0.95
(933)
400 28 1 8 0

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