1. von Heijne,G., & Teder,A. (1973) Kinetics of the Decomposition of Aqueous Chlorine Dioxide Solutions. Acta Chem.Scand. 27, 4018-4019.
2. von Heijne.G., & Blomberg,C. (1976) Kinetic Aspects of the DNA Helix-Cruciform Transition. J.theor.Biol. 63, 347-353.
3. Blomberg,C., von Heijne,G., & Nilsson,L. (1977) Description of Some Processes in Protein Synthesis From a Statistical Mechanical Point of View. Ann.Isr.Phys.Soc. 2, 970-973.
4. von Heijne,G., Nilsson,L., & Blomberg,C. (1977) Translation and Messenger RNA Secondary Structure. J.theor.Biol. 68, 321-329.
5. von Heijne,G., & Blomberg,C. (1977) The ß-structure: Inter-strand Correlations. J.Mol.Biol. 117, 821-824.
6. von Heijne,G., & Blomberg,C. (1978) Some Global ß-sheet Characteristics. Biopolymers 17, 2033-2037.
7. von Heijne,G., Nilsson,L., & Blomberg,C. (1978) Models for mRNA Translation: Theory versus Experiment. Eur.J.Biochem. 92, 397-402.
8. von Heijne,G., Blomberg,C., & Baltscheffsky,H. (1978) Early Evolution of Cellular Electron Transport: Molecular Models for the Ferredoxin-Rubredoxin-Flavodoxin Region. Origins of Life 9, 27-37.
9. Baltscheffsky,H., von Heijne,G., & Blomberg,C. (1978) Protein Secondary Structure and the Molecular Evolution of Biological Electron Transport.inMatsubara,H. & Yamanaka,T. (eds.): Evolution of Protein Molecules. Japan Scientific Societies Press. pp. 141-147.
10. von Heijne,G., Leimar,O., & Blomberg,C. (1978) On the Emergence of New Function in Primitive Proteins. J.theor.Biol. 75, 167-180.
11. von Heijne,G., & Blomberg,C. (1979) The Concentration Dependence of the Error Frequencies and Some Related Quantities in Protein Synthesis. J.theor.Biol. 78, 113-120.
12. von Heijne,G., & Blomberg,C. (1979) Trans-Membrane Translocation of Proteins: The Direct Transfer Model. Eur.J.Biochem. 97, 175-181.
13. von Heijne,G. (1980) Trans-Membrane Translocation of Proteins: A Detailed Physico-Chemical Analysis. Eur.J.Biochem. 103, 431-438.
14. von Heijne,G. (1980) A Sequence Correlation Between Oppositely Charged Residues in Secreted Proteins. Biochem.Biophys.Res.Comm. 93, 82-86.
15. Blomberg,C., von Heijne,G., & Leimar,O. (1981) Competition, Coexistence, and Irreversibility in Models of Early Molecular Evolution.inWolman,Y. (ed.): Origin of Life. Reidel Publishing Co. pp.385-392.
16. von Heijne,G. (1981) On the Hydrophobic Nature of Signal Sequences. Eur.J.Biochem. 116, 419-422.
17. von Heijne,G. (1981) Membrane Proteins: The Amino Acid Composition of Membrane-Penetrating Segments. Eur.J.Biochem. 120, 275-278.
18. von Heijne,G. (1981) Models for Trans-Membrane Translocation of Proteins. Biochem.Soc.Symp. 46, 259-273.
19. von Heijne,G., & Savageau,M. (1982) RNA Splicing: Advantages of Parallel Processing. J.theor.Biol. 98, 563-574.
20. von Heijne,G. (1982) Signal Sequences are not Uniformly Hydrophobic. J.Mol.Biol. 159, 537-541.
21. von Heijne,G. (1982) A Theoretical Study of the Attenuation Control Mechanism. J.theor.Biol. 97, 227-238.
22 von Heijne,G. (1983) Patterns of Amino Acids near Signal-Sequence Cleavage Sites. Eur.J.Biochem. 133, 17-21.
23. Flinta,C., von Heijne,G., & Johansson,J. (1983) Helical Sidedness and the Distribution of Polar Residues in Trans-membrane Helices. J.Mol.Biol. 168, 193-196.
24. von Heijne,G. (1984) How Signal Sequences Maintain Cleavage Specificity. J.Mol.Biol. 173, 243-251.
25. von Heijne,G. (1984) Analysis of the Distribution of Charged Residues in the N-terminal Region of Signal Sequences: Implications for Protein Export in Prokaryotic and Eukaryotic Cells. EMBO J. 3, 2315-2318.
26. von Heijne,G. (1985) Structural and Thermodynamic Aspects of the Transfer of Proteins Into and Across Membranes.In Current Topics in Membranes and Transport 24, 151-179.
27. von Heijne,G. (1985) "Theoretical Experiments" on Amino Acid and Nucleotide Sequences: Three Case-Studies. Biomed.Biochim.Acta 6, 903-911.
28. von Heijne,G. (1985) Signal Sequences: The Limits of Variation. J.Mol.Biol. 184, 99-105.
9. Liljenström,H., von Heijne,G., Blomberg,C., & Johansson,J. (1985) The tRNA Cycle and Its Relation to the Rate of Protein Synthesis. Eur.Biophys.J. 12, 115-119.
30. Persson,B., Flinta,C., von Heijne,G., & Jörnvall,H. (1985) Structures of N-terminally Acetylated Proteins. Eur.J.Biochem. 152, 523-527.
31. von Heijne,G. (1985) Ribosome - SRP - Signal Sequence Interactions: The Relay Helix Hypothesis. FEBS Lett. 190, 1-5.
32. Flinta,C., Persson,B., Jörnvall,H., & von Heijne,G. (1986) Sequence Determinants of Cytosolic N-terminal Protein Processing. Eur.J.Biochem. 154, 193-196.
33. von Heijne,G. (1986) Towards a Comparative Anatomy of N-terminal Topogenic Protein Sequences. J.Mol.Biol. 189, 239-242.
34. von Heijne,G. (1986) Why Mitochondria Need a Genome. FEBS Lett. 198, 1-4.
35. Liljenström,H., & von Heijne,G. (1987) Translation Rate Modification by Preferential Codon Usage: Intragenic Position Effects. J.theor.Biol. 124, 43-55.
36. von Heijne,G. (1986) Mitochondrial Targeting Sequences May Form Amphiphilic Helices. EMBO J. 5, 1335-1342.
37. von Heijne,G. (1986) A New Method for Predicting Signal Sequence Cleavage Sites. Nucl.Acids Res. 14, 4683-4690.
38. von Heijne,G. (1986) Net N-C Charge Imbalance may be Important for Signal Sequence Function in Bacteria. J.Mol.Biol. 192, 287-290.
39. von Heijne,G. (1986) The Distribution of Positively Charged Residues in Bacterial Inner Membrane Proteins Correlates With the Trans-Membrane Topology. EMBO J. 5, 3021-3027.
40. von Heijne,G., Blomberg,C., & Liljenström,H. (1987) Theoretical Modelling of Protein Synthesis. J.theor.Biol. 125, 1-14.
41. von Heijne,G. (1987) SIGPEP - A Sequence Database for Secretory Signal Peptides. Protein Sequence and Data Analysis 1, 41-42.
42. von Heijne,G., & Segrest,J. (1987) The Leader Peptides of Bacteriorhodopsin and Halorhodopsin are Potential Amphipathic Helices. FEBS Lett. 213, 238-240.
43. von Heijne,G., & Uhlén,M. (1987) Homology to Region X from Staphylococcal Protein A is not Unique to Cell Surface Proteins. J.theor.Biol. 127, 373-376.
44. von Heijne,G. (1987) Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit? Academic Press, 188pp.
45. von Heijne,G., Wickner,W., & Dalbey,R. (1988) The Cytoplasmic Domain of Escherichia coli Leader Peptidase is a Translocation Poison Sequence. Proc.Natl.Acad.Sci.USA 85, 3363-3366.
46. von Heijne,G., & Gavel,Y. (1988) Topogenic Signals in Integral Membrane Proteins. Eur.J.Biochem. 174, 671-678.
47. von Heijne,G. (1988) Sequence Determinants of Protein Sorting Into and Across Membranes. In Op den Kamp,J.A.F. (Ed) Membrane Biogenesis. NATO ASI Series H-16, Springer Verlag. pp. 307-322
48. von Heijne,G. (1988) Transcending the Impenetrable: How Proteins Come to Terms with Membranes. Biochim.Biophys.Acta. 947, 307-333.
49. Gavel, Y., Nilsson,L., & von Heijne,G. (1988) Mitochondrial Targeting Sequences: Why 'Non-Amphiphilic' Peptides May Still be Amphiphilic. FEBS Letters 235, 173-177.
50. von Heijne,G. (1988) Getting Sense out of Sequence Data. Nature 333, 605-608.
51. von Heijne,G. (1988) Role of the Signal Peptide in Protein Export. ISI Atlas of Science 1, 205-209.
52. von Heijne,G. (1988) Topogenic Signals in Membrane Protein Assembly. Proceedings of the 14th International Union of Biochemistry Congress.
53. von Heijne,G., Steppuhn,J., & Herrmann,R.G. (1989) Domain Structure of Mitochondrial and Chloroplast Targeting Peptides. Eur.J.Biochem. 180, 535-545.
54. von Heijne,G. (1989) The Structure of Signal Peptides from Bacterial Lipoproteins. Protein Engineering 2, 531-534.
55. von Heijne,G., & Abrahmsén,L. (1989) Species-Specific Variation in Signal Peptide Design: Implications for Protein Secretion in Foreign Hosts. FEBS Lett. 244, 439-446.
56. von Heijne,G. (1989) Control of Topology and Mode of Assembly of a Polytopic Membrane Protein by Positively Charged Residues. Nature 341, 456-458.
57. von Heijne,G. (1989) Structure of Targeting Peptides for Organellar Protein Import. Proceedings of the VIIIth International Congress on Photosynthesis. Kluwer Academic Publishers, Dordrecht.
58. Gavel,Y., & von Heijne,G. (1990) Sequence Differences Between Glycosylated and Non glycosylated Asn-X-Thr/Ser Acceptor Sites. Protein Engineering 3, 433-442.
59. von Heijne,G. (1990) The Signal Peptide. J.Membr.Biol. 115, 195-201.
60. Franzén,L-G., Rochaix,J-D., & von Heijne,G. (1990) Chloroplast Transit Peptides from the Green Alga Chlamydomonas reinhardtii Share Features with Both Mitochondrial and Higher Plant Presequences. FEBS Lett. 260, 165-168.
61. Gavel,Y., & von Heijne,G. (1990) Cleavage-site Motifs in Mitochondrial Targeting Peptides. Protein Engineering 4, 33-37.
62. Gavel,Y., & von Heijne, G. (1990) A Conserved Cleavage-Site Motif in Chloroplast Transit Peptides. FEBS Lett. 261, 455-458.
63. von Heijne, G. (1990) Protein Targeting Signals. Current Opinion in Cell Biology 2, 604-608.
64. Nilsson,IM., & von Heijne,G. (1990) Fine-tuning the Topology of a Polytopic Membrane Protein: Role of Positively and Negatively Charged Amino Acids. Cell, 62, 1135-1141.
65. Bilgin,N., Lee,J.I., Zhu,H., Dalbey,R., & von Heijne,G. (1990) Mapping of Catalytically Important Domains in Escherichia coli Leader Peptidase. EMBO J., 9, 2717-2722.
66. von Heijne,G., & Manoil,C. (1990) Membrane Proteins: From Sequence to Structure. Protein Engineering 4, 109-112.
67. Keegstra,K., & von Heijne,G. (1990) Transport of Proteins into Chloroplasts. In Herrmann,R. (ed.): Plant Gene Research: Cell Organelles. Springer Verlag. pp. 353-370.
68. von Heijne, G. (1990) Signals for Protein Import into Organelles. In Herrmann,R.G. & Larkins,B.O. (Eds.) "Plant Molecular Biology 2". NATO ASI series A, vol. 212, pp.583-593.
69. von Heijne,G. (1991) Cleavage-sites in Protein Targeting Signals. In Jörnvall,H., Höög,J-O., & Gustavsson,A-M. (Eds.) "Methods in Protein Sequence Analysis", Birkhäuser Verlag, Basel. pp. 231-238.
70. Nilsson, IM. & von Heijne,G. (1991) A de novo Designed Signal Peptide Cleavage Cassette Functions in vivo. J.Biol.Chem. 266, 3408-3410.
71. von Heijne,G. (1991) Proline-kinks in Transmembrane a-helices. J.Mol.Biol. 218, 499-503.
72. von Heijne,G. (1991) Computer Analysis of DNA and Protein Sequences. Eur.J.Biochem., 199, 253-256.
73. von Heijne,G. & Nishikawa,K. (1991) Chloroplast Transit Peptides: The Perfect Random Coil? FEBS Lett. 278, 1-3.
74. Wilson,I.B.H., Gavel,Y., & von Heijne,G. (1991) Amino Acid Distributions Around O-linked Glycosylation Sites. Biochem.J. 275, 529-534.
75. Gavel,Y., Steppuhn,J., Herrmann,R. & von Heijne,G. (1991) The "Positive-Inside Rule" Applies to Thylakoid Membrane Proteins. FEBS Lett. 282, 41-46.
76. von Heijne,G., Liljeström,P., Mikus,P., Andersson,H., & Ny,T. (1991) The Efficiency of the Uncleaved Secretion Signal in the Plasminogen Activator Inhibitor Type 2 Protein Can Be Enhanced by Point Mutations that Increase Its Hydrophobicity. J.Biol.Chem 266, 15240-15243.
77. Andersson,H., & von Heijne,G. (1991) A 30 Residues Long "Export Initiation Domain" Adjacent to the Signal Sequence is Critical for Protein Translocation Across the Inner Membrane of Escherichia coli. Proc.Natl.Acad.Sci USA 88, 9751-9754.
78. von Heijne,G., Hirai,T., Klösgen,R-B., Steppuhn,J., Keegstra,K., Herrmann,R. (1991) CHLPEP- A Database of Chloroplast Transit Peptides. Plant Molecular Biology Reporter 9, 104-126.
79. von Heijne,G. (1992) Sequence Determinants for Protein Import Into Chloroplasts and Thylakoid Membrane Protein Assembly. In Clarkson,D.T. and Cooke,D.T. (eds.) Transport and Receptor Proteins of Plant Membranes. Plenum Press, New York, pp. 195-199.
80. von Heijne,G. (1991) Protein Targeting - Basic Concepts. In The Encyclopedia of Human Biology, vol.6, pp. 237-243. Academic Press.
81. von Heijne,G. (1991) DNA, RNA, and Protein Sequences. Analysis by Computer. In The Encyclopedia of Human Biology, vol.3., pp.163-167. Academic Press.
82. Andersson,H., Bakker,E., & von Heijne,G. (1992) Different Positively Charged Amino Acids Have Similar Effects on the Topology of a Polytopic Transmembrane Protein in E. coli. J.Biol.Chem. 267, 1491-1495.
83. von Heijne, G. (1992) Cleavage-Site Motifs if Protein Targeting Sequences. In Genetic Engineering, Principles and Methods, vol.14. Plenum Press, New York. pp. 1-11.
84. Nilsson, IM., & von Heijne, G. (1992) A Signal Peptide With a Proline Next to the Cleavage Site Inhibits Leader Peptidase When Present in a sec Independent Protein. FEBS Lett. 299, 243-246.
85. von Heijne, G. (1992) Sequence Determinants of Membrane Protein Topology. In Neupert,W & Lill, R. (Eds.) Membrane Biogenesis and Protein Targeting. Elsevier, Amsterdam. pp.75-84.
86. von Heijne, G. (1994) Decoding the Signals of Membrane Protein Sequences. In White, S. (Ed.) Membrane Protein Structure: Experimental Approaches. Oxford University Press, New York. pp. 27-40.
87. von Heijne, G. (1992) Membrane Protein Structure Prediction: Hydrophobicity Analysis and the "Positive Inside" Rule. J.Mol.Biol. 225, 487-494.
88. Gavel, Y., & von Heijne, G. (1992) The Distribution of Charged Amino Acids in Mitochondrial Inner Membrane Proteins Suggests Different Modes of Membrane Integration for Nuclearly and Mitochondrially Encoded Proteins. Eur.J.Biochem. 205, 1207-1215.
89. Johansson, M., Nilsson, IM., & von Heijne, G. (1993) Positively Charged Amino Acids Placed Next to a Signal Sequence Block Protein Translocation More Efficiently in Escherichia coli than in Mammalian Microsomes. Mol.Gen.Genet., 239, 251-256.
90. von Heijne, G. (1993) Design of Protein Targeting Signals and Membrane Protein Engineering. In Wrede, P. & Schneider, G. (Eds.) Concepts of Protein Engineering and Design, pp. 263-279. Walter de Gruyter, Berlin.
91. Wallin, E., Wettergren, C., Hedman, F., & von Heijne, G. (1993) Fast Needleman-Wunsch Scanning of Sequence Databanks on a Massively Parallel Computer. CABIOS 9, 117-118.
92. von Heijne, G. (1992) Assembly of Escherichia Coli Inner Membrane Proteins: Sec-Dependent and Sec-Independent Membrane Insertion. In Pullman, B. & Pullman, A. (Eds.): Membrane Proteins: Structure and Function. Kluwer Publishers. pp. 449-455.
93. Andersson, H., & von Heijne, G. (1993) Sec-dependent and Sec-independent Assembly of E. coli Inner Membrane Proteins: The Topological Rules Depend on Chain Length. EMBO J. 12, 683-691.
94. von Heijne,G. (1994) Signals for Protein Targeting Into and Across Membranes. In Maddy, A.H., & Harris, J.R. (Eds.) Membrane Biogenesis. Plenum Publishing Corporation, New York, pp. 1-19.
95. Dalbey, R.E., & von Heijne, G. (1992) Signal Peptidases in Prokaryotes and Eukaryotes: A New Protease Family. TIBS 17, 474-478.
96. von Heijne, G. (1993) Targeting Signals and Mechanisms of Protein Insertion Into Membranes. In Wirtz, K.A. & Gustafsson, J-Å (Eds.) New Developments in Lipid-Protein Interactions and Receptor Function. NATO ASI Series, vol. A246, pp. 175-182. Plenum Publishing Corporation.
97. Cramer, W.A., Engelman, D.M., von Heijne, G., and Rees, D. (1992) Forces Involved in the Assembly and Stabilization of Membrane Proteins. FASEB J. 6, 3397-3402.
98. Nilsson, IM., and von Heijne, G. (1993) Determination of the Distance Between the Oligosaccharyl Transferase Active Site and the ER Membrane. J.Biol.Chem. 268, 5798-5801.
99. Nilsson, IM., Gafvelin, G., and von Heijne, G. (1993) Different Sec-Requirements for Signal Peptide Cleavage and Protein Translocation in a Model E. coli Protein. FEBS Lett. 318, 7-10.
100. Whitley, P., Nilsson, L., and von Heijne, G. (1993) A 3D-Model for the Membrane Domain of Escherichia coli Leader Peptidase Based on Disulphide Mapping. Biochemistry 32, 8534-8539.
101. Sipos, L., and von Heijne, G. (1993) Predicting the Topology of Eukaryotic Membrane Proteins. Eur. J. Biochem. 213, 1333-1340.
102. Andersson, H., and von Heijne, G. (1993) Position-specific Asp-Lys Pairing Can Affect Signal Sequence Function and Membrane Protein Topology. J. Biol. Chem. 268, 21389-21393.
103. Whitley, P., and von Heijne, G. (1995) Membrane Protein Assembly. In Dalbey, R. (Ed.) Membrane Organization and Biogenesis in Prokaryotic Organisms. JAI Press, pp. 1-16.
104. von Heijne, G. (1994) Membrane Proteins: From Sequence to Structure. Annu. Rev. Biophys. Biomol. Struct. 23, 167-192.
105. Whitley, P., and von Heijne, G. (1993) The DsbA-DsbB System Affects the Formation of Disulfide Bonds in Periplasmic But Not in Intramembraneous Protein Domains. FEBS Lett. 332, 49-51.
106. von Heijne, G. (1993) Assembly of Integral Membrane Proteins. In Op den Kamp, J.A.F. (Ed) Biological Membranes: Structure, Biogenesis and Dynamics. NATO ASI Series, vol. H82, pp.199-206. Springer Verlag, Berlin.
107. von Heijne, G. (1993) Membrane Protein Assembly: Can Protein-Lipid Interactions Explain the ÒPositive InsideÓ Rule? In Torriani, Silver & Yagil (Eds.) Molecular Biology of Phosphate in Microorganisms. ASM, pp. 247-250.
108. von Heijne, G. (1996) Computer-Assisted Identification of Protein Sorting Signals and Prediction of Membrane Protein Topology and Structure. In Villar, H.O. (Ed.) Advances in Computational Biology. JAI Press, pp. 1-14.
109. von Heijne, G. (1996) Targeting Signals for Protein Import Into Mitochondria and Other Subcellular Organelles. In Hartl, F-U. (Ed.) Advances in Molecular and Cell Biology, vol. 17., pp. 1-12. JAI Press, Inc.
110. Andersson, H., and von Heijne, G. (1994) Membrane Protein Topology: Effects of *µH+ on the Translocation of Charged Residues Explain the "Positive Inside" Rule. EMBO J. 13, 2267-2272.
111. Gafvelin, G., and von Heijne, G. (1994) Topological "Frustration" in Multi-Spanning E. coli Inner Membrane Proteins. Cell 77, 401-412.
112. von Heijne, G. (1996) Prediction of Transmembrane Protein Topology. In Sternberg, M. (Ed.) Prediction of Protein Structure - A Practical Approach, pp. 101-109. Oxford University Press.
113. Cheng, S., Cao, G., Whitley, P., von Heijne, G., Kuhn, A., and Dalbey, R.E. (1994) Synergistic Insertion of Two Hydrophobic Regions Drives sec Independent Membrane Protein Assembly. J. Biol. Chem. 269, 26898-26903.
114. Nilsson, IM., Whitley, P., von Heijne, G. (1994) The C-terminal Ends of Internal Signal and Signal-Anchor Sequences are Positioned Differently in the ER Translocase. J. Cell Biol. 126, 1127-1132.
115. Andersson, H., and von Heijne, G. (1994) Positively Charged Residues Influence the Degree of Sec-Dependence in Protein Translocation Across the E. coli Inner Membrane. FEBS Lett. 347, 169-172.
116. von Heijne, G. (1994) Sec-Independent Protein Insertion Into the Inner E. coli Membrane: A Phenomenon in Search of an Explanation. FEBS Lett. 346, 69-72.
117. von Heijne, G. (1994) Protein Sorting Signals: Simple Peptides with Complex Functions. In Jollés & Jörnvall (Eds.) Interface Between Chemistry and Biochemistry. Birkhäuser Verlag, in press.
118. Claros, M.G., and von Heijne, G. (1994) TopPred II: An Improved Software For Membrane Protein Structure Predictions. CABIOS 10, 685-686.
119. Whitley, P., Zander, T., Ehrmann, M., Haardt, M., Bremer, E., and von Heijne, G. (1994) Sec-Independent Translocation of a 100-Residues Long Periplasmic N-Terminal Tail in the E. coli Inner Membrane Protein ProW. EMBO J. 13, 4653-4661.
120. von Heijne, G. (1995) Membrane Protein Assembly: Rules of the Game. BioEssays 17, 25-30.
121. Whitley, P., Nilsson, IM., and von Heijne, G. (1994) De novo Design of Integral Membrane Proteins. Nature Struct.Biol. 1, 858-862.
122. Sääf, A., Andersson, H., Gafvelin, G., and von Heijne, G. (1995) SecA-Dependence of the Translocation of a Large Periplasmic Loop in the E. coli MalF Inner Membrane Protein is a Function of Sequence Context. Mol.Membr.Biol. 12, 209-215.
123. von Heijne, G. (1995) Membrane Protein Topogenesis in Escherichia coli. In Rothman, S.S. (Ed.) Membrane Protein Transport, vol. 3., pp. 201-214. JAI Press.
124. Hirsch, S., Muckel, E., Heemeyer, F., von Heijne, G., and Soll, J. (1994) A Receptor Component of the Chloroplast Protein Translocation Machinery. Science 266, 1989-1992.
125. von Heijne, G. (Editor) Signal Peptidases. RG Landes Press (1994).
126. Nielsen, H., Engelbrecht, J., von Heijne, G., and Brunak, S. (1996) Defining a Homology Threshold for a Functional Protein Sequence Pattern: The Signal Peptide Cleavage Site. PROTEINS: Struct. Funct. Genet. 24, 165-177.
127. Dalbey, R.D., Kuhn, A., and von Heijne, G. (1995). Directionality in protein translocation across membranes: The N-tail phenomenon. Trends Cell Biol. 5, 380-383.
128. Wallin, E., and von Heijne, G. (1995) Properties of N-terminal tails in G-protein coupled receptors - A statistical study. Protein Engineer. 8, 693-698.
129. Whitley, P., Sääf, A., Gafvelin, G., Johansson, M., Wallin, E., and von Heijne, G. (1995) Membrane protein anchors and polytopic determinants. Biochem.Soc.Trans., 23,965-967.
130. Nilsson, IM., Whitley, P., and von Heijne, G. (1996) Glycosylation mapping of the interaction between topogenic sequences and the ER translocase. In Op den Kamp, J.A.F. (Ed) Biological Membranes: Structure, Biogenesis and Dynamics. NATO ASI Series H, vol. 96, pp.9-14. Springer Verlag, Berlin.
131. van Klompenburg, W., von Heijne, G., and de Kruijff, B. (1995) A quantitative assay to determine the amount of signal peptidase I in E.coli and the orientation of membrane vesicles. Mol.Membr.Biol. 12, 349-353.
132. Whitely, P., Gafvelin, G., and von Heijne, G. (1995) Sec-independent translocation of the periplasmic N-terminal tail of an E. coli inner membrane protein: Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation signal. J.Biol.Chem. 270, 29831-29835.
133. Whitley, P., Nilsson, I.M., and von Heijne, G. (1996) A Nascent Secretory Protein May Traverse the Ribosome/ER translocase Complex as an Extended Chain. J.Biol.Chem. 271, 6241-6244.
134. Whitley, P., Grahn, E., Kutay, U., Rapoport, T.A., and von Heijne, G. (1996) A 12 residues long poly-leucine tail is sufficient to anchor syntaptobrevin to the ER membrane. J.Biol.Chem. 271, 7583-7586.
135. Mingarro, I., Whitley, P., Lemmon, M.A., and von Heijne, G. (1996) Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix. A rapid way to map helix-helix interactions in integral membrane proteins. Protein Sci. 5, 1339-1341.
136. Gafvelin, G., Sakaguchi, M., Andersson, H., and von Heijne, G. (1997) Topological rules for membrane protein assembly in eukaryotic cells. J.Biol.Chem. 272, 6119-6127.
137. van Klompenburg, W., Nilsson, IM., von Heijne, G., and de Kruijff, B. (1997) Anionic phospholipids are determinants of membrane protein topology. EMBO J. 16, 4261-4266.
138. Sääf, A., Wallin, E., and von Heijne, G. (1998) Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranes. Eur.J.Biochem.251, 821-829.
139. Whitley, P., and von Heijne, G. (1997) What can glycosylation mapping tell us about membrane proteins assembly and structure? In Hamasaki & Mihara (Eds.): Membrane proteins: Structure, function and expression control. pp. 117-126.
140. von Heijne, G. (1997) Evolution of protein sorting signals. In Schenk, H.E.A. (Ed.): Intertaxonic combination and symbiotic adaptation. Tübingen, pp.191-194.
141. Nielsen, H., Engelbrecht, J., Brunak, S. and von Heijne, G. (1997) A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Prot.Engineer. 10, 1-6.
142. Johansson, M. and von Heijne, G. (1996) Membrane topology of Kch, a putative K+ channel from E. coli. J.Biol.Chem. 271, 25912-25915.
143. Braun, P., Persson, B., Kaback, H.R. and von Heijne, G. (1997) Alanine insertion scanning mutagenesis of lactose permease transmembrane helices: Identification of a structurally and functionally important segment in helix III. J.Biol.Chem. 272, 29566-29571.
144. Kiefer, H., Krieger, J., Olszewski, J.D., von Heijne, G., Prestwich, G.D. and Breer, H. (1996) Expression of an olfactory receptor in E. coli: Purification, reconstitution, and ligand binding. Biochemistry 35, 16077-16084.
145. Glick, B.S. and von Heijne, G. (1996) Saccharomyces cerevisiae mitochondria lack a bacterial-type Sec machinery. Protein Sci. 5, 2651-2652.
146. von Heijne, G. (1997) Principles of membrane protein assembly and structure. Progr.Biophys.Mol.Biol., 66, 113-139.
147. Andersson, H., Nilsson, IM. and von Heijne, G. (1996) Calnexin can interact with N-linked glycans located close to the endoplasmic reticulum membrane. FEBS Lett. 397, 321-324.
148. de Gier, J-W.L., Mansournia, P., Valent, Q.A., Phillips, G.J., Lurink, J. and von Heijne, G. (1996) Assembly of a cytoplasmic membrane proteins in Escherichia coli is dependent on the signal recognition particle. FEBS Lett. 399, 307-309.
149. Wallin, E., Tsukihara, T., Yoshikawa, S., von Heijne, G. and Elofsson, A. (1997) Architecture of helix bundle membrane proteins: An analysis of cytochrome c oxidase from bovine mitochondria. Protein Sci.6, 808-815.
150. von Heijne, G. (1997) Getting greasy: How transmembrane polypeptide segments integrate into the lipid bilayer. Mol.Microbiol., 24, 249-253.
151. Nielsen, H., Engelbrecht, J., Brunak, S. and von Heijne, G. (1997) A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Int. J. Neural Systems, in press.
152. Mothes, W., Heinrich, S., Graf, R., Nilsson, IM., von Heijne, G., Brunner, J. and Rapoport, T.A. (1997) Molecular mechanism of membrane protein integration into the endoplasmic reticulum. Cell, 89, 523-533.
153. Nilsson, IM., Sääf, A., Whitley, P., Gafvelin, G., Waller, C., and von Heijne, G. (1998) Proline-induced disruption of a transmembrane alpha-helix in its natural environment. J.Mol.Biol., 284, 1165-1175.
154. Claros, M., Brunak, S., and von Heijne G. (1997) Prediction of N-terminal sorting signals. Curr. Opinion Struct. Biol.7, 394-398.
155. Cserzö, M., Wallin, E., Simon, I., von Heijne, G., and Elofsson, A. (1997) Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: The Dense Alignment Surface method. Protein Engineer., 10, 673-676.
156. de Gier, J-W., Valent, Q.A., von Heijne, G., and Luirink, J. (1997) The E. coli SRP: preferences of a targeting factor. FEBS Lett., 408, 1-4.
157. Valent, Q.A., de Gier, J-W., von Heijne, G., Kendall, D.A., ten Hagen-Jongman, C.M., Oudega, B., and Luirink, J. (1997) Nascent membrane and presecretory proteins associate with signal recognition particle and trigger factor. Mol. Microbiol., 25, 53-64.
158. Mingarro, I., de Gier, J-W., von Heijne, G., Braun, P., and Whitley, P. (1998) Membrane Protein Assembly. In Chapman, D. and Haris, P.I. (Eds.): Biomembrane Structures. IOS Press, Amsterdam, pp. 228-244.
159. Mingarro, I., Elofsson, A., and von Heijne, G. (1997) Helix-helix packing in a membrane-like environment. J. Mol. Biol., 272, 633-641.
160. Schneider, G., Sjöling, S., Wallin, E., Wrede, P., Glaser, E., and von Heijne, G. (1998) Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides. PROTEINS: Struct. Funct. Genet. 30, 49-60.
161. Mingarro, I., von Heijne, G., and Whitley, P. (1997) Membrane protein engineering. TIBTECH, 15, 432-437.
162. van Klompenburg, W., Ridder, A.N.J.A., van Raalte, A.L.J., Killian, A.J., von Heijne, G., and de Kruijff, B. (1997) In vitro membrane integration of leader peptidase depends on the Sec machinery and anionic phospholipids and can occur post-translationally. FEBS Lett. 413, 109-114.
163. Wallin, E., and von Heijne, G. (1998) Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms. Protein Sci.7, 1029-1038.
164. Valent, Q.A., Scotti, P.A., High, S., de Gier, J.W.L., von Heijne, G., Lentzen, G., Wintermeyer, Oudega, B., and Luirink, J. (1998) The E. coli SRP and Sec targeting pathways converge at the translocon. EMBO J.9, 2504-2512.
165. Sonnhammer, E.L.L., von Heijne, G., and Krogh, A. (1998) A hidden Markov model for predicting transmembrane helices in protein sequences. Intell. Syst. Mol.Biol. 6, 175-182.
166. Seshadri, K., Wallin, E., Garemyr, R., von Heijne, G., and Elofsson, A. (1998) Architecture of ß-barrel membrane proteins: Structural analysis of trimeric porins. Protein Sci. 7, 2026-2032.
167. van Klompenburg, W., Paetzel, M., de Jong, J.M., Dalbey, R.E., Demel, R.A., von Heijne, G., and de Kruijff, B. (1998) Phosphatidylethanolamine mediates insertion of the catalytic domain of leader peptidase in membranes. FEBS Lett.431, 75-79.
168. Ota, K., Sakaguchi, M., von Heijne, G., Hamasaki, N., and Mihara, K. (1998) Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins. Molecular Cell 2, 495-503.
169. de Gier, J.W., Scotti, P.A., Sääf, A., Valent, Q.A., Kuhn, A., Luirink, J., and von Heijne, G. (1998) Differential use of the SRP-translocase targeting pathway for inner membrane protein assembly in Escherichia coli. Proc.Natl.Acad.Sci. USA, in press.
170. Monné, M., Nilsson, IM., Johansson, M., Elmhed, N., and von Heijne, G. (1998) Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. J.Mol.Biol., 284, 1177-1183.
171. Nilsson, IM., and von Heijne, G. (1998) Breaking the camel's back: Proline-induced turns in a model transmembrane helix. J.Mol.Biol., 284, 1185-1189.
172. Sääf, A., Monné, M., de Gier, JW., and von Heijne, G. (1998) Membrane topology of the 60 kDa Oxa1p homologue from Escherichia coli. J.Biol.Chem. 273, 30415-30418.
173. von Heijne, G. (1998) News & Views: The life and death of a signal peptide. Nature 396, 111-112.
174. van Geest, M., Nilsson, IM., von Heijne, G., and Lolkelma, J.S. (1999) Insertion of a bacterial secondary transport protein into the ER membrane. J.Biol.Chem, in press.