#The inner membrane proteome of 225 bacteria. Columns H-AB show the number of proteins with an assigned location for different numbers of transmembrane helices. Organism Group Genes Predicted membrane proteins Fraction predicted membrane proteins Assigned membrane proteins Fraction assigned membrane proteins 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 >20 Buchnera aphidicola str. APS (Acyrthosiphon pisum) Gammaproteobacteria 574 87 0.15 42 0.48 0 4 3 4 6 7 2 2 4 4 0 2 2 0 1 0 0 1 0 0 0 Buchnera aphidicola str. Sg (Schizaphis graminum) Gammaproteobacteria 545 88 0.16 43 0.49 1 3 3 3 5 10 1 4 4 3 0 2 0 2 1 1 0 0 0 0 0 Methanopyrus kandleri AV19 Euryarchaeota 1687 284 0.17 24 0.08 1 3 1 2 1 6 4 1 0 2 1 2 0 0 0 0 0 0 0 0 0 Aeropyrum pernix K1 Crenarchaeota 2694 464 0.17 68 0.15 3 2 3 1 8 19 6 5 4 5 1 4 2 3 0 0 1 1 0 0 0 Buchnera aphidicola str. Bp (Baizongia pistaciae) Gammaproteobacteria 504 87 0.17 43 0.49 0 3 4 3 5 7 2 4 3 5 0 3 0 2 1 0 0 1 0 0 0 Xanthomonas oryzae pv. oryzae KACC10331 Gammaproteobacteria 4637 835 0.18 269 0.32 17 46 24 26 21 35 8 11 10 14 9 30 8 5 2 3 0 0 0 0 0 Photorhabdus luminescens subsp. laumondii TTO1 Gammaproteobacteria 4683 864 0.18 355 0.41 9 31 30 43 28 51 20 28 14 25 14 44 3 12 1 2 0 0 0 0 0 Methanocaldococcus jannaschii DSM 2661 Euryarchaeota 1770 329 0.19 46 0.14 2 4 1 4 4 6 3 2 7 6 1 3 2 1 0 0 0 0 0 0 0 Azoarcus sp. EbN1 Betaproteobacteria 4598 870 0.19 272 0.31 25 39 24 25 20 39 13 18 16 13 4 22 2 8 2 0 0 0 1 0 1 Neisseria gonorrhoeae FA 1090 Betaproteobacteria 2002 380 0.19 125 0.33 7 8 14 13 9 20 3 9 5 11 6 10 3 5 0 2 0 0 0 0 0 Deinococcus radiodurans Deinococcus-Thermus 3102 595 0.19 189 0.32 14 18 9 17 16 40 8 16 8 16 4 12 2 5 1 1 0 0 1 0 1 Gluconobacter oxydans 621H Alphaproteobacteria 2664 514 0.19 173 0.34 16 14 8 17 16 25 8 11 6 13 10 22 5 0 2 0 0 0 0 0 0 Synechococcus sp. WH 8102 Cyanobacteria 2517 490 0.19 123 0.25 7 10 13 15 10 21 9 7 4 9 4 6 1 6 1 0 0 0 0 0 0 Zymomonas mobilis subsp. mobilis ZM4 Alphaproteobacteria 1998 389 0.19 125 0.32 12 9 5 12 9 26 5 7 5 12 3 14 2 3 1 0 0 0 0 0 0 Mycobacterium tuberculosis CDC1551 Actinobacteria 4189 816 0.19 166 0.20 8 12 10 16 18 31 7 10 8 9 5 17 4 6 3 2 0 0 0 0 0 Neisseria meningitidis Z2491 Betaproteobacteria 2065 406 0.20 132 0.33 7 7 16 12 10 22 5 8 6 9 9 9 5 5 0 2 0 0 0 0 0 Neisseria meningitidis MC58 Betaproteobacteria 2025 403 0.20 130 0.32 7 8 15 13 10 22 3 9 7 8 9 7 5 5 0 2 0 0 0 0 0 Burkholderia mallei ATCC 23344 Betaproteobacteria 4764 950 0.20 425 0.45 19 44 28 36 27 59 23 28 11 35 19 68 5 19 2 1 0 1 0 0 0 Mycobacterium tuberculosis H37Rv Actinobacteria 3991 801 0.20 168 0.21 8 10 11 18 18 32 7 10 7 10 4 18 4 7 2 2 0 0 0 0 0 Mycobacterium bovis AF2122/97 Actinobacteria 3920 793 0.20 166 0.21 8 10 12 18 16 32 7 10 7 10 4 18 4 6 2 2 0 0 0 0 0 Thermus thermophilus HB8 Deinococcus-Thermus 2238 455 0.20 138 0.30 6 13 8 8 8 34 6 11 7 15 3 9 3 3 1 1 1 0 1 0 0 Xylella fastidiosa 9a5c Gammaproteobacteria 2832 577 0.20 134 0.23 6 14 13 13 13 21 5 9 5 10 4 11 2 5 2 1 0 0 0 0 0 Chlorobium tepidum TLS Bacteroides/Cholorobi 2252 460 0.20 101 0.22 4 7 11 11 9 14 8 12 6 4 2 9 1 2 0 1 0 0 0 0 0 Archaeoglobus fulgidus DSM 4304 Euryarchaeota 2407 492 0.20 92 0.19 6 6 2 5 4 18 2 11 6 11 3 12 4 2 0 0 0 0 0 0 0 Methanococcus maripaludis S2 Euryarchaeota 1722 352 0.20 73 0.21 2 9 2 3 4 15 5 5 2 6 3 12 3 2 0 0 0 0 0 0 0 Shigella flexneri 2a str. 301 Gammaproteobacteria 4443 909 0.20 546 0.60 18 60 32 60 44 80 22 41 25 42 29 70 10 7 2 3 0 1 0 0 0 Aquifex aeolicus VF5 Aquificae 1553 319 0.21 110 0.34 9 13 11 13 9 13 7 7 6 4 3 6 0 7 0 2 0 0 0 0 0 Halobacterium sp. NRC-1 Euryarchaeota 2605 536 0.21 122 0.23 7 11 7 7 7 15 9 7 11 19 5 10 1 3 1 1 1 0 0 0 0 Candidatus Blochmannia floridanus Gammaproteobacteria 583 120 0.21 57 0.48 2 6 6 5 3 10 5 3 3 6 2 2 0 2 1 0 0 1 0 0 0 Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis Gammaproteobacteria 611 127 0.21 60 0.47 1 7 6 7 5 13 2 1 4 5 4 4 0 0 1 0 0 0 0 0 0 Pirellula sp. Planctomycetes 7325 1523 0.21 195 0.13 16 31 21 16 11 19 8 14 9 7 12 21 7 2 0 0 0 0 1 0 0 Mycobacterium avium subsp. paratuberculosis str. k10 Actinobacteria 4350 907 0.21 180 0.20 7 15 14 15 27 38 6 8 8 7 7 16 4 6 1 1 0 0 0 0 0 Helicobacter pylori 26695 Epsilonproteobacteria 1553 326 0.21 99 0.30 5 6 10 12 8 15 8 4 2 9 3 8 3 3 0 3 0 0 0 0 0 Shigella flexneri 2a str. 2457T Gammaproteobacteria 4068 854 0.21 536 0.63 16 57 32 58 43 80 21 40 24 40 27 75 10 7 2 3 0 1 0 0 0 Escherichia coli O157:H7 Gammaproteobacteria 5447 1148 0.21 641 0.56 18 68 40 66 51 88 21 47 28 49 35 100 10 10 4 5 0 1 0 0 0 Thermus thermophilus HB27 Deinococcus-Thermus 2210 467 0.21 147 0.31 7 14 8 8 10 38 8 9 8 16 4 7 3 3 1 1 1 0 1 0 0 Pseudomonas syringae pv. tomato str. DC3000 Gammaproteobacteria 5607 1186 0.21 536 0.45 34 91 31 40 42 94 25 25 20 29 15 68 7 10 2 2 0 0 0 0 1 Nocardia farcinica IFM 10152 Actinobacteria 5936 1266 0.21 286 0.23 7 17 13 24 30 58 10 14 12 12 10 42 8 25 1 2 0 0 0 0 1 Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough Deltaproteobacteria 3531 758 0.21 284 0.37 33 58 19 27 22 40 11 10 11 22 6 12 5 6 1 0 0 0 0 0 1 Bordetella pertussis Tohama I Betaproteobacteria 3447 743 0.22 298 0.40 10 21 21 25 26 69 19 23 13 24 7 23 3 9 2 1 0 1 0 0 1 Escherichia coli O157:H7 EDL933 Gammaproteobacteria 5349 1154 0.22 649 0.56 22 70 40 64 53 87 22 48 29 49 34 101 10 10 4 5 0 1 0 0 0 Thermoplasma volcanium GSS1 Euryarchaeota 1526 330 0.22 76 0.23 0 0 2 4 4 10 4 7 2 7 5 15 5 9 1 1 0 0 0 0 0 Xanthomonas axonopodis pv. citri str. 306 Gammaproteobacteria 4427 961 0.22 336 0.35 45 46 24 32 22 41 11 9 14 18 8 44 8 8 2 3 0 0 0 0 1 Haemophilus influenzae Rd KW20 Gammaproteobacteria 1709 371 0.22 179 0.48 5 17 9 20 21 30 10 11 7 16 12 11 5 2 2 1 0 0 0 0 0 Dehalococcoides ethenogenes 195 Chloroflexi 1580 343 0.22 84 0.24 3 6 2 10 5 24 5 7 6 4 3 1 2 4 1 0 0 1 0 0 0 Methanothermobacter thermautotrophicus str. Delta H Euryarchaeota 1869 407 0.22 62 0.15 5 5 2 3 2 11 6 8 3 7 4 2 1 3 0 0 0 0 0 0 0 Mycoplasma pneumoniae M129 Firmicutes 688 150 0.22 22 0.15 4 1 0 0 2 9 1 0 1 2 0 2 0 0 0 0 0 0 0 0 0 Gloeobacter violaceus PCC 7421 Cyanobacteria 4430 966 0.22 217 0.22 19 24 21 18 15 37 13 15 6 8 8 21 2 6 0 3 0 1 0 0 0 Sulfolobus solfataricus P2 Crenarchaeota 2994 657 0.22 129 0.20 6 3 2 6 0 28 5 11 5 9 8 33 3 6 2 0 0 0 1 0 1 Methylococcus capsulatus str. Bath Gammaproteobacteria 2959 652 0.22 230 0.35 18 25 21 20 15 33 12 16 8 14 13 23 2 7 0 3 0 0 0 0 0 Pyrococcus furiosus DSM 3638 Euryarchaeota 2065 456 0.22 90 0.20 3 2 4 7 8 27 3 8 4 9 2 9 2 2 0 0 0 0 0 0 0 Silicibacter pomeroyi DSS-3 Alphaproteobacteria 4252 939 0.22 308 0.33 10 24 13 20 41 71 17 20 14 26 11 27 3 5 3 2 0 0 0 0 1 Bordetella bronchiseptica RB50 Betaproteobacteria 4994 1106 0.22 436 0.39 15 32 25 35 38 97 31 37 16 44 10 35 4 11 3 1 0 1 0 0 1 Chromobacterium violaceum ATCC 12472 Betaproteobacteria 4407 977 0.22 449 0.46 39 63 37 48 34 57 21 30 15 32 12 45 4 9 1 2 0 0 0 0 0 Borrelia burgdorferi B31 Spirochaetes 1639 364 0.22 51 0.14 3 6 2 6 4 8 2 3 4 4 2 4 2 1 0 0 0 0 0 0 0 Mesorhizobium loti MAFF303099 Alphaproteobacteria 7281 1618 0.22 604 0.37 34 46 39 41 40 178 35 47 18 48 11 44 5 14 2 2 0 0 0 0 0 Pyrobaculum aerophilum str. IM2 Crenarchaeota 2605 579 0.22 68 0.12 3 1 1 3 2 22 4 4 6 5 1 10 3 1 0 1 0 0 1 0 0 Mannheimia succiniciproducens MBEL55E Gammaproteobacteria 2384 530 0.22 254 0.48 10 22 15 31 27 41 9 19 8 24 10 22 9 3 2 1 0 1 0 0 0 Caulobacter crescentus CB15 Alphaproteobacteria 3737 836 0.22 253 0.30 20 33 20 29 13 43 11 14 10 13 6 32 1 4 3 1 0 0 0 0 0 Xylella fastidiosa Temecula1 Gammaproteobacteria 2036 456 0.22 132 0.29 7 15 12 16 12 21 5 8 3 11 3 9 3 4 2 1 0 0 0 0 0 Methanosarcina mazei Goe1 Euryarchaeota 3371 755 0.22 159 0.21 17 14 13 14 13 27 9 9 4 10 7 13 3 3 0 1 1 1 0 0 0 Brucella melitensis 16M Alphaproteobacteria 3198 717 0.22 289 0.40 15 15 18 30 25 65 20 19 11 18 9 31 3 4 2 1 1 0 0 0 2 Streptococcus thermophilus CNRZ1066 Firmicutes 1915 431 0.23 126 0.29 8 10 13 12 9 26 5 15 3 13 2 8 1 1 0 0 0 0 0 0 0 Wolbachia endosymbiont of Drosophila melanogaster Alphaproteobacteria 1195 269 0.23 68 0.25 2 2 7 5 6 10 5 6 5 3 4 8 0 3 1 1 0 0 0 0 0 Thermoplasma acidophilum Euryarchaeota 1478 333 0.23 84 0.25 0 0 1 2 3 17 2 5 5 12 6 16 3 10 0 2 0 0 0 0 0 Haemophilus ducreyi 35000HP Gammaproteobacteria 1717 387 0.23 148 0.38 5 12 17 16 15 30 4 10 6 9 9 8 5 0 2 0 0 0 0 0 0 Streptococcus pyogenes SSI-1 Firmicutes 1861 420 0.23 122 0.29 5 12 6 10 14 24 9 12 3 10 6 9 1 1 0 0 0 0 0 0 0 Nanoarchaeum equitans Kin4-M Nanoarchaeota 536 121 0.23 7 0.06 0 1 0 1 2 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 Porphyromonas gingivalis W83 Bacteroides/Cholorobi 1909 431 0.23 85 0.20 3 15 3 7 3 15 6 3 8 8 4 10 0 0 0 0 0 0 0 0 0 Xanthomonas campestris pv. campestris str. ATCC 33913 Gammaproteobacteria 4181 944 0.23 309 0.33 29 45 19 27 23 34 11 13 17 17 9 42 10 7 3 2 0 0 0 0 1 Pseudomonas putida KT2440 Gammaproteobacteria 5350 1208 0.23 581 0.48 32 84 35 39 42 84 33 28 21 45 17 92 11 13 2 2 0 0 0 0 1 Helicobacter pylori J99 Epsilonproteobacteria 1491 337 0.23 102 0.30 6 7 9 11 8 15 10 4 1 9 3 10 3 3 0 3 0 0 0 0 0 Streptococcus pyogenes MGAS315 Firmicutes 1865 422 0.23 123 0.29 4 13 6 12 14 24 8 11 4 12 4 10 0 1 0 0 0 0 0 0 0 Mycoplasma genitalium G-37 Firmicutes 480 109 0.23 24 0.22 4 1 0 1 2 9 1 0 0 4 0 2 0 0 0 0 0 0 0 0 0 Coxiella burnetii RSA 493 Gammaproteobacteria 2046 465 0.23 127 0.27 4 10 8 10 16 13 1 5 10 6 6 20 2 12 2 1 0 0 1 0 0 Shewanella oneidensis MR-1 Gammaproteobacteria 4778 1088 0.23 389 0.36 35 70 29 36 22 65 12 27 5 24 16 33 6 6 2 1 0 0 0 0 0 Pyrococcus abyssi Euryarchaeota 1784 407 0.23 90 0.22 2 3 2 8 3 28 3 7 4 13 3 7 1 4 0 1 1 0 0 0 0 Escherichia coli CFT073 Gammaproteobacteria 5379 1228 0.23 648 0.53 18 67 38 63 52 92 22 46 25 61 32 96 17 11 4 3 0 1 0 0 0 Parachlamydia sp. UWE25 Chlamydiae/Verrucomicrobia 2031 464 0.23 99 0.21 5 4 5 12 8 15 6 8 7 6 8 9 1 3 1 1 0 0 0 0 0 Agrobacterium tumefaciens str. C58 Uwash Alphaproteobacteria 5402 1235 0.23 563 0.46 26 50 34 30 52 165 39 38 22 33 13 44 3 8 2 2 0 0 0 1 1 Bordetella parapertussis Betaproteobacteria 4185 957 0.23 384 0.40 12 31 22 30 31 88 25 35 15 41 10 27 3 8 3 1 1 0 0 0 1 Sinorhizobium meliloti Alphaproteobacteria 6205 1422 0.23 588 0.41 27 38 24 44 44 165 32 52 23 39 15 57 7 15 3 1 0 0 1 0 1 Wolbachia endosymbiont strain TRS of Brugia malayi Alphaproteobacteria 805 185 0.23 56 0.30 1 2 7 4 4 11 4 2 3 5 4 4 1 3 0 0 1 0 0 0 0 Sulfolobus tokodaii str. 7 Crenarchaeota 2826 650 0.23 96 0.15 5 0 2 6 0 16 3 7 4 13 6 22 5 4 0 0 0 1 1 0 1 Campylobacter jejuni RM1221 Epsilonproteobacteria 1838 423 0.23 145 0.34 8 13 10 17 11 20 11 5 8 10 6 18 5 1 0 2 0 0 0 0 0 Rickettsia conorii str. Malish 7 Alphaproteobacteria 1374 317 0.23 79 0.25 1 5 8 5 11 8 3 5 7 6 1 11 2 4 1 1 0 0 0 0 0 Streptococcus pyogenes MGAS8232 Firmicutes 1845 426 0.23 124 0.29 5 13 6 10 14 25 8 11 4 12 4 10 1 1 0 0 0 0 0 0 0 Burkholderia pseudomallei K96243 Betaproteobacteria 5729 1324 0.23 549 0.41 21 61 32 42 38 88 26 34 16 50 15 88 9 21 3 3 0 1 1 0 0 Mycobacterium leprae Actinobacteria 1605 371 0.23 70 0.19 4 7 4 9 7 14 2 6 4 4 1 6 0 2 0 0 0 0 0 0 0 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 Fusobacteria 2067 479 0.23 149 0.31 6 9 5 10 12 33 7 10 10 16 6 22 3 0 0 0 0 0 0 0 0 Prochlorococcus marinus str. MIT 9313 Cyanobacteria 2265 525 0.23 120 0.23 6 11 12 12 8 27 5 10 4 9 3 6 1 5 1 0 0 0 0 0 0 Streptococcus thermophilus LMG 18311 Firmicutes 1889 438 0.23 124 0.28 6 9 11 12 8 29 7 15 3 12 2 8 1 1 0 0 0 0 0 0 0 Streptomyces coelicolor A3(2) Actinobacteria 8154 1891 0.23 512 0.27 18 39 25 45 34 144 13 24 18 32 11 57 11 39 0 1 1 0 0 0 0 Salmonella enterica subsp. enterica serovar Typhi str. CT18 Gammaproteobacteria 4766 1106 0.23 571 0.52 13 66 39 60 47 75 21 42 21 42 28 87 13 9 4 3 0 1 0 0 0 Ralstonia solanacearum Betaproteobacteria 5116 1188 0.23 425 0.36 16 62 39 34 31 50 30 28 12 39 10 53 8 9 2 2 0 0 0 0 0 Acinetobacter sp. ADP1 Gammaproteobacteria 3325 773 0.23 316 0.41 12 20 26 25 23 50 12 17 14 23 15 59 6 10 1 2 0 0 0 0 1 Streptococcus pneumoniae TIGR4 Firmicutes 2094 490 0.23 154 0.31 7 13 8 13 12 47 6 13 5 17 2 10 1 0 0 0 0 0 0 0 0 Bradyrhizobium japonicum USDA 110 Alphaproteobacteria 8317 1956 0.24 680 0.35 38 86 39 54 37 140 44 54 22 36 24 78 7 15 5 1 0 0 0 0 0 Helicobacter hepaticus ATCC 51449 Epsilonproteobacteria 1875 442 0.24 121 0.27 7 14 12 8 13 17 8 2 7 8 5 10 3 5 0 2 0 0 0 0 0 Brucella suis 1330 Alphaproteobacteria 3273 773 0.24 290 0.38 16 18 13 24 20 73 24 21 10 14 12 30 2 7 2 2 0 0 0 0 2 Nostoc sp. PCC 7120 Cyanobacteria 6132 1449 0.24 342 0.24 68 44 23 34 21 53 14 24 8 14 13 14 3 7 0 1 0 1 0 0 0 Picrophilus torridus DSM 9790 Euryarchaeota 1535 363 0.24 103 0.28 1 2 1 3 1 22 4 9 3 10 6 25 2 8 1 4 0 0 1 0 0 Nitrosomonas europaea ATCC 19718 Betaproteobacteria 2461 582 0.24 160 0.27 10 23 16 18 11 25 9 8 5 10 6 11 1 3 1 2 0 0 0 0 1 Treponema pallidum subsp. pallidum str. Nichols Spirochaetes 1031 244 0.24 41 0.17 4 1 2 5 1 10 4 7 1 3 0 3 0 0 0 0 0 0 0 0 0 Bdellovibrio bacteriovorus HD100 Deltaproteobacteria 3583 849 0.24 203 0.24 11 37 15 15 17 34 10 13 11 12 9 15 2 1 0 1 0 0 0 0 0 Streptomyces avermitilis MA-4680 Actinobacteria 7673 1820 0.24 464 0.25 18 36 14 39 34 127 19 17 13 27 10 52 18 38 0 1 0 1 0 0 0 Synechococcus elongatus PCC 6301 Cyanobacteria 2525 600 0.24 168 0.28 23 17 12 12 16 30 10 9 9 7 4 11 1 5 0 2 0 0 0 0 0 Leptospira interrogans serovar lai str. 56601 Spirochaetes 4725 1123 0.24 156 0.14 14 21 10 11 14 30 7 9 4 8 6 16 2 2 2 0 0 0 0 0 0 Streptococcus pyogenes MGAS10394 Firmicutes 1886 450 0.24 123 0.27 5 13 6 11 10 26 9 9 3 18 2 9 1 1 0 0 0 0 0 0 0 Vibrio vulnificus CMCP6 Gammaproteobacteria 4537 1084 0.24 513 0.47 45 102 27 48 43 76 17 28 23 32 21 40 6 2 2 1 0 0 0 0 0 Pseudomonas aeruginosa PAO1 Gammaproteobacteria 5566 1333 0.24 574 0.43 31 85 32 39 51 84 28 29 13 39 20 94 13 11 2 2 0 0 0 0 1 Erwinia carotovora subsp. atroseptica SCRI1043 Gammaproteobacteria 4472 1072 0.24 601 0.56 16 84 45 51 47 99 23 39 15 52 25 78 7 12 3 4 0 1 0 0 0 Streptococcus pneumoniae R6 Firmicutes 2043 490 0.24 152 0.31 6 12 8 15 12 47 7 14 5 15 2 9 0 0 0 0 0 0 0 0 0 Chlamydia muridarum Nigg Chlamydiae/Verrucomicrobia 911 219 0.24 54 0.25 1 3 5 2 2 11 4 6 4 8 4 3 1 0 0 0 0 0 0 0 0 Streptococcus pyogenes M1 GAS Firmicutes 1696 408 0.24 121 0.30 5 12 6 10 12 28 7 12 1 14 3 9 1 1 0 0 0 0 0 0 0 Thermotoga maritima MSB8 Thermotogae 1846 445 0.24 147 0.33 7 12 7 7 8 54 13 9 5 13 5 5 1 0 0 1 0 0 0 0 0 Yersinia pestis CO92 Gammaproteobacteria 4083 988 0.24 480 0.49 17 46 35 46 36 93 19 36 25 43 15 48 6 10 2 2 0 0 0 1 0 Salmonella enterica subsp. enterica serovar Typhi Ty2 Gammaproteobacteria 4323 1047 0.24 567 0.54 13 65 39 60 46 75 21 41 20 43 27 87 13 9 4 3 0 1 0 0 0 Agrobacterium tumefaciens str. C58 Alphaproteobacteria 5301 1286 0.24 565 0.44 31 51 28 36 41 174 37 40 20 35 12 42 5 7 2 2 0 0 0 1 1 Bartonella henselae str. Houston-1 Alphaproteobacteria 1488 361 0.24 105 0.29 3 8 10 9 9 18 5 8 5 5 6 10 1 4 2 1 0 0 0 0 1 Geobacillus kaustophilus HTA426 Firmicutes 3540 859 0.24 257 0.30 14 28 20 21 21 45 13 19 7 28 5 22 5 5 2 2 0 0 0 0 0 Campylobacter jejuni subsp. jejuni NCTC 11168 Epsilonproteobacteria 1634 397 0.24 148 0.37 9 12 12 15 11 20 11 8 6 10 5 22 4 1 0 2 0 0 0 0 0 Haloarcula marismortui ATCC 43049 Euryarchaeota 4240 1033 0.24 213 0.21 15 15 13 19 14 38 24 17 5 16 7 14 6 5 0 2 1 0 1 0 1 Escherichia coli K12 Gammaproteobacteria 4242 1035 0.24 656 0.63 19 75 42 64 47 87 24 46 27 54 33 106 13 10 4 4 0 1 0 0 0 Prochlorococcus marinus subsp. pastoris str. CCMP1986 Cyanobacteria 1712 418 0.24 84 0.20 5 6 8 5 7 16 5 9 3 7 1 8 1 3 0 0 0 0 0 0 0 Vibrio cholerae O1 biovar eltor str. N16961 Gammaproteobacteria 3828 936 0.24 423 0.45 20 93 31 35 32 63 11 30 17 29 13 34 7 5 1 1 0 1 0 0 0 Bacteroides thetaiotaomicron VPI-5482 Bacteroides/Cholorobi 4816 1178 0.24 282 0.24 48 41 11 25 14 33 4 10 7 19 7 52 5 5 0 1 0 0 0 0 0 Chlamydia trachomatis D/UW-3/CX Chlamydiae/Verrucomicrobia 894 219 0.24 55 0.25 0 3 5 2 2 12 4 6 5 6 5 4 1 0 0 0 0 0 0 0 0 Staphylococcus epidermidis RP62A Firmicutes 2526 619 0.25 194 0.31 9 14 9 12 20 30 8 15 6 14 13 25 7 9 2 0 0 0 0 0 1 Salmonella enterica subsp. enterica serovar Paratypi A str. ATCC 9150 Gammaproteobacteria 4093 1003 0.25 564 0.56 15 61 40 59 47 76 19 38 23 39 30 85 14 11 3 4 0 0 0 0 0 Photobacterium profundum Gammaproteobacteria 5480 1349 0.25 546 0.40 27 91 32 48 43 84 20 38 16 51 27 47 9 7 4 1 0 1 0 0 0 Vibrio parahaemolyticus RIMD 2210633 Gammaproteobacteria 4832 1191 0.25 510 0.43 37 92 31 49 35 81 11 41 21 36 19 45 5 3 3 0 0 1 0 0 0 Idiomarina loihiensis L2TR Gammaproteobacteria 2628 648 0.25 238 0.37 21 34 24 28 18 26 11 13 8 15 9 22 6 1 1 0 0 0 0 0 1 Pasteurella multocida subsp. multocida str. Pm70 Gammaproteobacteria 2014 497 0.25 242 0.49 5 22 17 22 18 44 14 19 11 24 12 17 9 4 3 1 0 0 0 0 0 Salmonella typhimurium LT2 Gammaproteobacteria 4554 1124 0.25 620 0.55 12 74 41 65 50 80 22 44 23 38 33 106 13 10 5 3 0 1 0 0 0 Mesoplasma florum L1 Firmicutes 683 169 0.25 39 0.23 0 1 0 1 1 13 1 3 3 11 2 2 1 0 0 0 0 0 0 0 0 Bacteroides fragilis YCH46 Bacteroides/Cholorobi 4625 1145 0.25 238 0.21 34 33 8 20 8 28 7 11 4 25 8 42 4 4 0 2 0 0 0 0 0 Leifsonia xyli subsp. xyli str. CTCB07 Actinobacteria 2030 504 0.25 122 0.24 6 7 9 8 10 26 6 11 7 12 6 8 3 2 1 0 0 0 0 0 0 Vibrio vulnificus YJ016 Gammaproteobacteria 5028 1250 0.25 529 0.42 31 120 29 52 32 82 22 27 18 38 19 46 7 3 2 1 0 0 0 0 0 Thermosynechococcus elongatus BP-1 Cyanobacteria 2475 618 0.25 154 0.25 25 15 10 8 12 25 10 9 5 6 12 8 2 4 0 3 0 0 0 0 0 Yersinia pestis biovar Medievalis str. 91001 Gammaproteobacteria 4142 1036 0.25 490 0.47 20 48 34 50 39 88 23 36 23 44 15 50 6 9 3 1 0 0 0 1 0 Yersinia pestis KIM Gammaproteobacteria 4090 1023 0.25 481 0.47 19 47 32 48 38 89 20 36 21 47 15 48 6 10 2 2 0 0 0 1 0 Listeria innocua Firmicutes 3043 762 0.25 252 0.33 12 21 15 19 19 55 13 19 7 28 6 26 4 6 1 0 0 0 0 0 1 Wolinella succinogenes Epsilonproteobacteria 2044 513 0.25 219 0.43 21 53 12 15 20 31 11 9 4 13 6 14 3 6 0 1 0 0 0 0 0 Borrelia garinii PBi Spirochaetes 932 234 0.25 51 0.22 3 5 2 5 6 8 1 5 2 6 2 3 2 1 0 0 0 0 0 0 0 Thermococcus kodakaraensis KOD1 Euryarchaeota 2306 579 0.25 89 0.15 3 7 3 3 5 20 5 14 4 12 3 8 0 2 0 0 0 0 0 0 0 Staphylococcus epidermidis ATCC 12228 Firmicutes 2485 625 0.25 200 0.32 10 15 9 11 21 30 11 14 8 13 12 25 7 11 2 0 0 0 0 0 1 Bifidobacterium longum NCC2705 Actinobacteria 1727 435 0.25 154 0.35 9 10 5 18 5 39 9 8 5 14 7 22 0 2 0 1 0 0 0 0 0 Bacteroides fragilis NCTC 9343 Bacteroides/Cholorobi 4236 1067 0.25 238 0.22 31 33 8 21 8 28 8 11 4 24 8 44 5 3 0 2 0 0 0 0 0 Corynebacterium efficiens YS-314 Actinobacteria 2942 742 0.25 196 0.26 6 13 8 13 12 32 10 14 8 17 12 29 7 13 0 0 0 0 0 0 2 Propionibacterium acnes KPA171202 Actinobacteria 2297 582 0.25 185 0.32 7 6 11 16 13 38 7 18 10 16 7 25 6 4 0 1 0 0 0 0 0 Thermoanaerobacter tengcongensis MB4 Firmicutes 2588 658 0.25 160 0.24 12 16 3 14 7 46 13 10 6 14 6 9 2 1 0 1 0 0 0 0 0 Rhodopseudomonas palustris CGA009 Alphaproteobacteria 4815 1225 0.25 440 0.36 40 63 17 39 20 78 32 38 14 28 13 39 4 11 2 1 0 0 0 0 1 Legionella pneumophila str. Paris Gammaproteobacteria 3166 808 0.26 237 0.29 10 17 16 21 18 39 7 14 12 20 12 37 1 10 1 1 1 0 0 0 0 Legionella pneumophila str. Lens Gammaproteobacteria 2934 749 0.26 225 0.30 12 18 13 22 15 37 7 12 14 17 12 34 1 9 0 1 1 0 0 0 0 Yersinia pseudotuberculosis IP 32953 Gammaproteobacteria 4038 1031 0.26 504 0.49 14 53 35 50 39 93 21 40 25 45 15 53 6 10 2 2 0 0 0 1 0 Corynebacterium glutamicum ATCC 13032 Actinobacteria 3099 792 0.26 213 0.27 4 16 10 17 13 35 9 21 9 21 10 28 6 11 0 1 0 0 0 0 2 Streptococcus agalactiae 2603V/R Firmicutes 2124 543 0.26 176 0.32 4 21 8 13 18 32 11 19 7 17 5 16 1 4 0 0 0 0 0 0 0 Synechocystis sp. PCC 6803 Cyanobacteria 3176 819 0.26 218 0.27 34 24 14 10 13 41 12 18 11 7 7 18 2 5 0 2 0 0 0 0 0 Bacillus clausii KSM-K16 Firmicutes 4108 1060 0.26 367 0.35 14 33 18 26 24 119 14 20 10 28 9 27 10 10 1 0 1 0 0 1 2 Methanosarcina acetivorans str. C2A Euryarchaeota 4540 1173 0.26 212 0.18 23 15 12 11 13 52 8 22 6 17 7 15 1 8 0 1 0 0 1 0 0 Pyrococcus horikoshii OT3 Euryarchaeota 2061 534 0.26 87 0.16 5 5 2 5 4 28 1 3 9 8 3 10 2 1 0 1 0 0 0 0 0 Vibrio fischeri ES114 Gammaproteobacteria 3802 988 0.26 457 0.46 22 96 31 42 32 61 12 33 19 27 26 41 6 5 2 1 0 0 0 1 0 Symbiobacterium thermophilum IAM 14863 Actinobacteria 3337 869 0.26 253 0.29 12 31 13 16 24 56 14 21 14 15 4 18 5 7 0 2 0 0 0 1 0 Staphylococcus aureus subsp. aureus Mu50 Firmicutes 2733 713 0.26 217 0.30 8 17 9 14 18 37 10 18 13 18 13 19 7 13 2 0 0 0 0 0 1 Lactococcus lactis subsp. lactis Il1403 Firmicutes 2266 592 0.26 170 0.29 5 14 9 11 8 36 10 13 9 17 5 19 4 9 0 1 0 0 0 0 0 Staphylococcus aureus subsp. aureus MRSA252 Firmicutes 2656 696 0.26 222 0.32 6 16 8 15 17 42 8 19 12 18 15 23 8 12 2 0 0 0 0 0 1 Staphylococcus aureus subsp. aureus COL Firmicutes 2618 687 0.26 214 0.31 7 16 8 13 17 36 9 17 12 19 13 22 9 13 2 0 0 0 0 0 1 Prochlorococcus marinus subsp. marinus str. CCMP1375 Cyanobacteria 1882 494 0.26 86 0.17 5 8 8 7 8 15 4 10 4 7 2 4 0 4 0 0 0 0 0 0 0 Chlamydophila caviae GPIC Chlamydiae/Verrucomicrobia 1005 264 0.26 58 0.22 2 3 5 4 5 8 5 6 4 7 5 3 1 0 0 0 0 0 0 0 0 Geobacter sulfurreducens PCA Deltaproteobacteria 3447 909 0.26 303 0.33 31 76 20 16 21 38 11 19 13 14 7 20 6 7 0 3 0 1 0 0 0 Corynebacterium diphtheriae Actinobacteria 2272 600 0.26 150 0.25 6 10 5 10 14 29 6 15 6 9 10 16 6 5 2 0 0 0 0 0 1 Chlamydophila pneumoniae TW-183 Chlamydiae/Verrucomicrobia 1113 294 0.26 54 0.18 1 3 5 5 2 8 5 7 3 5 4 4 2 0 0 0 0 0 0 0 0 Staphylococcus aureus subsp. aureus N315 Firmicutes 2624 696 0.27 218 0.31 8 16 9 15 17 37 9 18 13 18 14 20 8 13 2 0 0 0 0 0 1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Gammaproteobacteria 2942 781 0.27 235 0.30 15 16 15 20 19 35 11 14 13 16 10 39 0 10 0 1 1 0 0 0 0 Chlamydophila pneumoniae AR39 Chlamydiae/Verrucomicrobia 1110 295 0.27 55 0.19 1 3 4 6 2 8 4 8 3 6 4 4 2 0 0 0 0 0 0 0 0 Streptococcus mutans UA159 Firmicutes 1960 523 0.27 147 0.28 6 14 9 12 21 27 7 16 3 17 5 6 1 3 0 0 0 0 0 0 0 Staphylococcus aureus subsp. aureus MW2 Firmicutes 2632 703 0.27 212 0.30 8 16 8 13 16 38 8 17 12 18 13 21 8 13 2 0 0 0 0 0 1 Clostridium acetobutylicum ATCC 824 Firmicutes 3848 1028 0.27 275 0.27 12 46 17 25 16 70 6 10 9 19 14 23 3 5 0 0 0 0 0 0 0 Enterococcus faecalis V583 Firmicutes 3265 873 0.27 254 0.29 8 19 12 19 28 57 12 30 7 29 4 23 2 4 0 0 0 0 0 0 0 Chlamydophila pneumoniae J138 Chlamydiae/Verrucomicrobia 1069 288 0.27 54 0.19 1 3 4 6 2 8 5 7 3 5 4 4 2 0 0 0 0 0 0 0 0 Mycoplasma penetrans HF-2 Firmicutes 1037 280 0.27 41 0.15 6 2 1 1 2 14 4 0 1 7 1 2 0 0 0 0 0 0 0 0 0 Desulfotalea psychrophila LSv54 Deltaproteobacteria 3236 874 0.27 269 0.31 14 52 13 19 16 55 16 16 4 18 12 18 7 7 1 1 0 0 0 0 0 Bacillus halodurans C-125 Firmicutes 4066 1099 0.27 307 0.28 11 37 19 22 17 84 11 18 11 28 9 29 4 3 2 1 0 0 0 0 1 Staphylococcus aureus subsp. aureus MSSA476 Firmicutes 2598 704 0.27 213 0.30 7 16 8 13 17 39 8 17 12 18 13 21 8 13 2 0 0 0 0 0 1 Lactobacillus acidophilus NCFM Firmicutes 1864 509 0.27 172 0.34 3 11 5 15 13 41 10 11 6 23 9 17 3 5 0 0 0 0 0 0 0 Listeria monocytogenes Firmicutes 2846 779 0.27 261 0.34 12 20 14 22 15 53 15 23 9 30 7 29 3 7 1 0 0 0 0 0 1 Bacillus licheniformis ATCC 14580 Firmicutes 4152 1144 0.28 365 0.32 10 39 21 26 19 66 14 34 10 44 14 48 5 13 1 0 0 0 0 0 1 Bacillus subtilis subsp. subtilis str. 168 Firmicutes 4106 1133 0.28 383 0.34 16 33 26 30 24 61 12 24 16 42 14 60 9 14 1 0 0 0 0 1 0 Bacillus anthracis str. A2012 Firmicutes 308 85 0.28 2 0.02 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Bacillus licheniformis DSM 13 Firmicutes 4196 1160 0.28 374 0.32 11 39 23 27 20 66 14 35 10 43 13 53 5 13 1 0 0 0 0 0 1 Lactobacillus plantarum WCFS1 Firmicutes 3059 846 0.28 273 0.32 12 15 13 24 19 39 15 19 12 38 11 40 6 10 0 0 0 0 0 0 0 Bartonella quintana str. Toulouse Alphaproteobacteria 1142 316 0.28 96 0.30 2 8 9 6 10 19 5 6 6 5 4 7 1 4 2 0 1 0 0 0 1 Streptococcus agalactiae NEM316 Firmicutes 2094 580 0.28 177 0.31 4 21 9 12 17 35 11 18 7 17 6 15 1 4 0 0 0 0 0 0 0 Mycoplasma mobile 163K Firmicutes 635 176 0.28 27 0.15 3 2 0 0 1 12 2 0 1 3 0 3 0 0 0 0 0 0 0 0 0 Chlamydophila pneumoniae CWL029 Chlamydiae/Verrucomicrobia 1052 292 0.28 55 0.19 1 3 4 6 2 8 5 7 3 5 5 4 2 0 0 0 0 0 0 0 0 Tropheryma whipplei TW08/27 Actinobacteria 783 218 0.28 46 0.21 3 3 1 5 3 10 3 6 4 2 2 4 0 0 0 0 0 0 0 0 0 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Spirochaetes 3658 1023 0.28 155 0.15 15 20 11 11 12 31 6 9 5 8 8 14 1 2 2 0 0 0 0 0 0 Listeria monocytogenes str. 4b F2365 Firmicutes 2821 789 0.28 254 0.32 12 19 15 21 17 50 16 20 8 30 7 28 3 6 1 0 0 0 0 0 1 Rickettsia typhi str. Wilmington Alphaproteobacteria 838 235 0.28 78 0.33 2 3 6 5 9 11 3 7 5 4 1 13 3 3 1 1 0 1 0 0 0 Ureaplasma parvum serovar 3 str. ATCC 700970 Firmicutes 611 172 0.28 29 0.17 2 1 0 0 1 8 0 5 2 7 2 1 0 0 0 0 0 0 0 0 0 Francisella tularensis subsp. tularensis Schu 4 Gammaproteobacteria 1603 452 0.28 154 0.34 1 10 10 12 11 22 8 5 4 11 12 32 5 8 2 0 0 0 1 0 0 Mycoplasma mycoides subsp. mycoides SC Firmicutes 1016 288 0.28 30 0.10 0 0 0 1 0 11 1 1 6 8 0 1 1 0 0 0 0 0 0 0 0 Bacillus cereus ATCC 14579 Firmicutes 5255 1504 0.29 421 0.28 14 48 27 26 24 74 15 27 19 45 15 59 14 11 1 2 0 0 0 0 0 Rickettsia prowazekii Alphaproteobacteria 834 239 0.29 81 0.34 1 4 9 3 9 10 2 6 6 7 1 14 3 3 1 1 1 0 0 0 0 Onion yellows phytoplasma OY-M Firmicutes 754 218 0.29 34 0.16 2 2 1 3 6 11 2 1 2 3 0 0 0 0 0 0 0 1 0 0 0 Tropheryma whipplei str. Twist Actinobacteria 808 234 0.29 46 0.20 3 3 1 5 3 9 3 6 5 2 0 6 0 0 0 0 0 0 0 0 0 Treponema denticola ATCC 35405 Spirochaetes 2767 804 0.29 185 0.23 15 25 4 17 9 65 6 14 5 6 2 15 2 0 0 0 0 0 0 0 0 Mycoplasma pulmonis Firmicutes 782 228 0.29 40 0.18 6 1 0 5 1 17 1 0 4 2 1 2 0 0 0 0 0 0 0 0 0 Bacillus cereus ATCC 10987 Firmicutes 5844 1709 0.29 437 0.26 12 48 24 24 24 86 18 32 17 48 16 59 12 13 2 2 0 0 0 0 0 Bacillus anthracis str. 'Ames Ancestor' Firmicutes 5617 1646 0.29 427 0.26 15 46 27 27 23 69 16 31 16 49 14 64 13 12 3 1 0 0 1 0 0 Bacillus anthracis str. Ames Firmicutes 5311 1560 0.29 425 0.27 14 46 27 27 22 69 16 31 16 49 14 64 13 12 3 1 0 0 1 0 0 Lactobacillus johnsonii NCC 533 Firmicutes 1821 539 0.30 192 0.36 5 14 5 18 19 39 7 14 9 19 8 25 4 6 0 0 0 0 0 0 0 Clostridium perfringens str. 13 Firmicutes 2723 806 0.30 217 0.27 10 18 15 16 14 37 12 18 12 21 4 29 7 4 0 0 0 0 0 0 0 Clostridium tetani E88 Firmicutes 2432 722 0.30 183 0.25 7 38 10 16 11 33 6 12 8 18 4 17 2 1 0 0 0 0 0 0 0 Oceanobacillus iheyensis HTE831 Firmicutes 3496 1040 0.30 273 0.26 12 23 8 23 16 67 13 18 15 17 11 25 14 8 1 0 0 0 0 0 2 Bacillus anthracis str. Sterne Firmicutes 5287 1587 0.30 441 0.28 14 49 27 29 25 74 16 34 14 50 15 64 13 12 2 2 0 0 1 0 0 Bacillus cereus ZK Firmicutes 5134 1558 0.30 458 0.29 16 54 26 24 29 81 18 32 17 54 15 63 11 14 2 2 0 0 0 0 0 Bacillus thuringiensis serovar konkukian str. 97-27 Firmicutes 5197 1583 0.30 452 0.29 17 51 26 29 26 78 16 34 17 55 15 58 13 12 2 2 0 0 1 0 0 Ehrlichia ruminantium str. Welgevonden Alphaproteobacteria 888 272 0.31 60 0.22 4 1 6 5 5 9 5 6 2 1 1 9 1 3 2 0 0 0 0 0 0 Anaplasma marginale str. St. Maries Alphaproteobacteria 949 295 0.31 60 0.20 3 2 6 6 3 13 3 5 3 2 2 8 1 2 1 0 0 0 0 0 0 Ehrlichia ruminantium str. Welgevonden CIRAD Alphaproteobacteria 958 301 0.31 60 0.20 4 1 6 5 4 9 6 6 2 1 1 9 2 2 1 1 0 0 0 0 0 Mycoplasma gallisepticum R Firmicutes 726 229 0.32 29 0.13 5 0 1 2 0 13 2 1 2 2 0 1 0 0 0 0 0 0 0 0 0 Ehrlichia ruminantium str. Gardel Alphaproteobacteria 950 301 0.32 60 0.20 4 1 6 5 3 10 6 6 2 1 1 9 1 3 1 1 0 0 0 0 0 Mycoplasma hyopneumoniae 232 Firmicutes 691 236 0.34 41 0.17 3 1 1 13 3 13 0 1 3 2 1 0 0 0 0 0 0 0 0 0 0